The first think I thought when I saw this quote was that there's a wall full of unicycles at the YCombinator/AnyBots office, and lots of people that ride them effectively.
From http://tlb.org/eunicycle.html:"Some time ago I built a self-balancing two-wheeled scooter. Since then I realized that two wheels are redundant, and only a single wheel is needed to make a ridable vehicle."