My entire industry (subset of healthcare) mostly uses a single application for 95% of our core business functions. That application is written in Visual FoxPro and is, predictably, pretty terrible. Obviously it isn't going to get better, either, but it'll be a decade or more before there's a serious competitor.
I'm not near the space any longer (in a former life, the healthcare industry was a big customer of our computer systems). But a significant portion of healthcare in the US used to use a proprietary language called MUMPS. https://en.wikipedia.org/wiki/MUMPS
Epic has been trying to move on for years, or so a recruiter told me half a decade ago. Their job posting now describes “Using leading-edge technologies and languages like JS, TS, and C#”, though I wouldn’t put a bait and switch past them.
MEDITECH, maybe others, had a proprietary operating system too. (We had a special deal to sell them hardware without an OS at a time when they were normally bundled.) Eventually they moved on to NT.
