I haven't used SQLite in production, but I've used a single installation of Postgres for some surprisingly high traffic websites, and it works amazingly well with essentially no tweaking. I agree that the vast majority of people using anything more complex very likely don't need to be.
My understanding is that herpes (both HSV1 and HSV2) are not actually bad but have enormous social stigma, which is the main problem. I wonder what can be done to address that, as an alternative strategy.
I have recurring cold sores next to my right eye. I had it in my eye as a kid as well. I could go blind any time I have it in my eye again. No joke - not exaggerating.
I got it very early as a kid, and kids are bad at not touching their face, so I most certainly moved it from my nose to my eye at some point.
I can also get it on my nose, in my nose, my lips, forehead. So far.
My kid is now almost 3, we were very careful, but he got it a few months ago, had it 3 times in the last three weeks. It destroys our life. We have a 6 month old, it could be life threatening for the little one if they just touch. And even if only mild, explain to a 6 month old he should not scratch his patch off his face...
That is if you have weak symptoms. You can have HSV1 herpes which reactivates on certain triggers like stress or environmental changes and takes a hold of your whole skin, causing overall itchiness and leading to hospitalization for treatment. These people have to take takes suppressants their whole lives which causes stress on the liver and kidneys.
A treatment of the root cause would be tremendous.
They are actually bad, with a risk of chronic latent infection that could extend to deeper in the brain, and also a strongly suspected link with the (still unknown) cause of Alzheimer's.
A significant part of the stigma comes from the fact that once caught, it’s for life. So curing it looks like the best way to also fix the social stigma.
I just started reading 'Skin in the Game' by Nassim Taleb. These kind of overpriced consulting contracts, where nobody in particular bears the downside risk of incompetence, fit into his framework well. Hiring Deloitte et al usually amounts to outsourcing responsibility, except the people who do the work also bear little or no long-term responsibility if things go bad. A 3-person startup, on the other hand, suffers from severe downside (at least in a business sense) if they mess something like this up.
